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目的观察长托宁作为麻醉前用药在小儿先心病介入治疗的临床效果。方法择期小儿先心病介入术40例,长托宁组(P组)和阿托品组(A组)各20例,两组分别给药0.01 mg/kg。结果给药后30 min P组的HR、MAP和T均无显著变化;P组的唾液分泌量、吸痰量及拔管后恶心呕吐发生率明显少于A组。结论长托宁作为小儿先心病介入治疗术前用药能够维持血流动力学稳定,有效抑制呼吸道分泌。
Objective To observe the clinical effect of penehyclidine hydrochloride as interventional therapy in congenital heart disease in children before anesthesia. Methods Elective cardiopulmonary bypass was performed in 40 patients, 20 patients in the penehyclidine group (group P) and 20 patients in the atropine group (group A), and each group was given 0.01 mg / kg. Results There was no significant change of HR, MAP and T in group P at 30 min after administration. The salivary secretion, sputum aspiration volume and the incidence of nausea and vomiting after extubation in group P were significantly less than those in group A. Conclusions Penehyclidine can be used as a pretreatment drug for pediatric congenital heart disease to maintain hemodynamic stability and effectively suppress respiratory secretion.