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长期接触高浓度石棉尘的工人,其肺癌死亡率高于未从事石棉工业的居民。本文目的在于研究苏联巴仁诺夫矿产的温石棉,在吸入染尘条件下,对实验动物的致癌作用。实验用天然温石棉尘,分散度在1微米以下占54%,1～5微米占42%,6～40微米占4%。染尘浓度为200毫克/米~3。每周自然吸入染尘5天,每天5小时半,共染尘18个月。染尘动物为非纯种大白鼠,共26只,分别在9～11 1/2月(5只)、12～13 1/2月(9只)、15～23月(10只)、26～27月(2只)自然死亡。对照组25只。均取肺脏做组织学检查。
Persons exposed to long-term high levels of asbestos dust have a higher lung cancer death rate than those not engaged in the asbestos industry. The purpose of this paper is to study the carcinogenicity of chrysotile in the Chubenov Mine in the Soviet Union to experimental animals under inhalation of dust. Experiment with natural chrysotile dust, the dispersion of 54% below 1 micron, 1 ~ 5 microns accounted for 42%, 6 ~ 40 microns accounted for 4%. Dyeing concentration of 200 mg / m ~ 3. Natural inhalation of dust 5 days a week, 5 hours and a half, a total of 18 months of dust. Dust-laden animals were non-purebred rats, with a total of 26 animals, ranging from 9 to 11 1/2 months (n = 5), 12 to 13 1/2 months (n = 9), 15 to 23 months ~ 27 months (2) Natural death. Control group 25. Take the lungs for histological examination.