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目的探讨胸腹腔镜联合食管癌根治术并辅助术后化疗治疗食管癌的临床分析。方法 45例食管癌患者,按照随机数字表法分为观察组(23例)和对照组(22例)。对照组患者采用传统切除术治疗,观察组患者采用胸腹腔镜联合手术并辅助术后化疗。比较两组手术治疗和并发症发生情况,并对两组患者随访12月后的生活质量评分进行比较。结果观察组患者手术时间为(4.62±1.06)h,明显长于对照组的(3.05±0.92)h(P<0.05);观察组患者术中出血量为(279.34±30.64)ml,少于对照组的(492.83±52.13)ml(P<0.05);观察组患者带管时间为(2.16±0.58)d、住院时间为(10.08±1.18)d,明显短于对照组的(5.08±0.61)、(18.19±2.91)d,差异均有统计学意义(P<0.05)。随访12个月后,观察组患者肺部感染情况明显少于对照组,差异有统计学意义(P<0.05);观察组患者生理机能、生理职能、身体疼痛、总体健康、精力、社会职能、情感职能、精神健康评分均优于对照组,差异有统计学意义(P<0.05)。结论胸腹腔镜联合食管癌根治术并辅助术后化疗治疗食管癌临床效果显著,可明显减少食管癌术后并发症,值得临床推广。
Objective To investigate the clinical analysis of thoracoscopic laparoscopic combined with esophageal cancer radical surgery and adjuvant postoperative chemotherapy for esophageal cancer. Methods Forty-five patients with esophageal cancer were divided into observation group (n = 23) and control group (n = 22) according to random number table. Patients in the control group were treated by conventional resection. Patients in the observation group were treated with thoraco-laparoscopic surgery combined with postoperative chemotherapy. The surgical treatment and complications were compared between the two groups, and the quality of life scores of the two groups were compared after 12 months of follow-up. Results The operation time in the observation group was (4.62 ± 1.06) h, which was significantly longer than that in the control group (3.05 ± 0.92) h (P <0.05). The bleeding volume in the observation group was (279.34 ± 30.64) ml less than that in the control group (492.83 ± 52.13) ml in the observation group (2.16 ± 0.58) d and (10.08 ± 1.18) d in the observation group, which was significantly shorter than that in the control group (5.08 ± 0.61) and ( 18.19 ± 2.91) d, the difference was statistically significant (P <0.05). After 12 months of follow-up, the lung infection in the observation group was significantly less than that in the control group (P <0.05). The physical function, physical function, body pain, general health, energy, social function, Emotional function, mental health scores were better than the control group, the difference was statistically significant (P <0.05). Conclusions Laparoscopic combined with esophageal cancer radical surgery and adjuvant postoperative chemotherapy for the treatment of esophageal cancer clinical effect is significant, can significantly reduce the postoperative complications of esophageal cancer, is worth clinical promotion.