目的:提高侵蚀性葡萄胎(侵葡)和绒毛膜癌(绒癌)的早期诊断和治愈率。方法:对2002年1月～2011年3月妊娠滋养细胞肿瘤患者36例进行回顾性分析。结果:36例妊娠滋养细胞肿瘤病例中25例为侵蚀性葡萄胎,11例为绒癌。11例行单纯化疗,19例行联合化疗,6例行化疗加手术治疗。Ⅰ期近期治愈率100.0%,Ⅱ期近期治愈率86.9%,Ⅲ期近期治愈率70.1%。结论:早期诊断、早期治疗、规范化疗是提高侵葡和绒癌治愈率的关健,必要时应辅以手术治疗。 OBJECTIVE: To improve the early diagnosis and cure rate of invasive hydatidiform mole (TAP) and choriocarcinoma (choriocarcinoma). Methods: From January 2002 to March 2011, 36 cases of gestational trophoblastic tumor were retrospectively analyzed. Results: Of the 36 cases of gestational trophoblastic tumor, 25 cases were invasive hydatidiform mole and 11 cases were choriocarcinoma. 11 cases of simple chemotherapy, 19 cases of combined chemotherapy, 6 cases of chemotherapy plus surgery. The recent cure rate was 100.0% in stage Ⅰ, the cure rate in stage Ⅱ was 86.9%, and the cure rate in stage Ⅲ was 70.1%. Conclusion: Early diagnosis, early treatment and standard chemotherapy are the key factors to improve the cure rate of invasion and choriocarcinoma. When necessary, surgery should be supplemented.