重复球囊瓣膜成形术治疗59~104岁主动脉瓣狭窄患者的结果

来源 :世界核心医学期刊文摘(心脏病学分册) | 被引量 : 0次 | 上传用户:missAma
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Balloon aortic valvuloplasty(BAV)may be considered a palliative procedure that is performed in patients who have severely symptomatic aortic stenosis and a prohibitive surgical risk. However, due to poor early survival rates, most previous studies have involved a single BAV procedure. We analyzed long-term outcomes in patients who had severe aortic stenosis and BAV that incorporated repeat procedures to maintain symptom relief and increase survival rate. We retrospectively analyzed 212 consecutive nonsurgical patients(59 to 104 years old)who had severe calcific aortic stenosis and underwent 282 cumulative BAV procedures. Demographic, procedural, and follow-up mortality data were collected. BAV was performed with single or incremental balloon dilatation to obtain a postprocedural transaortic gradient close to 1/3 of the baseline gradient. Peak transaortic gradient after BAV decreased from 55±22 to 20±11 mm Hg and aortic valve area increased from 0.6±0.2 to 1.2±0.3 cm2. Mean follow-up duration was 32±18 months. During follow-up,24%of patients underwent a second BAVand 9%of patients underwent a third BAV. Duration of symptom alleviation after the first, second, and third BAV procedures were 18±3, 15±4, and 10±3 months, respectively. Median survival after BAV was 35 months. Survival rates 1, 3, and 5 years after the procedure were 64%, 28%, and 14%respectively. Patients who underwent repeat BAV had higher 3-year survival rates than did patients who underwent 1 BAV(p=0.01). Therefore, repeat BAV is a viable treatment strategy in nonsurgical patients who have severe calcific aortic stenosis, because it provides a median survival of~3 years and maintains clinical improvement. Balloon aortic valvuloplasty (BAV) may be considered a palliative procedure that is performed in patients who have severely symp sympathetic aortic stenosis and a prohibitive surgical risk. However, due to poor early survival rates, most recent studies have involved a single BAV procedure. long-term outcomes in patients who had severe aortic stenosis and BAV that incorporated repeat procedures to maintain symptom relief and increase survival rate. We retrospectively analyzed 212 consecutive nonsurgical patients (59 to 104 years old) who had severe calcific aortic stenosis and underwent 282 cumulative BAV procedures. Demographic, procedural, and follow-up mortality data were collected. BAV was performed with single or incremental balloon dilatation to obtain a postprocedural transaortic gradient close to 1/3 of the baseline gradient. Peak transaortic gradient after BAV decreased from 55 ± 22 to 20 ± 11 mm Hg and aortic valve area increased from 0.6 ± 0.2 to 1.2 ± 0.3 cm2. Mean follow-u Duration follow up first, second and third BAV procedures were 18 ± 3, 15 ± 4, and 10 ± 3 months, respectively. Median survival after BAV was 35 months. Survival rates 1, 3, and 5 years after the procedure were 64%, 28%, and 14% respectively. 3-year survival rates than did patients who underwent 1 BAV (p = 0.01). Thus, repeat BAV is a viable treatment strategy in nonsurgical patients who have severe calcific aortic stenosis, because it provides a median survival of ~ 3 years and serves clinical improvement.
其他文献
为推进农业现代化和城乡统筹发展,拓展农业发展空间,促进农民创业增收,经湖南省人民政府同意,现就加快全省休闲农业发展提出以下意见。一、充分认识加快休闲农业发展的重要性
故障现象一辆行驶里程约为7.4万km的2013款宝马525Li车(配备N20发动机),客户反映该车起动困难(与平时相比,起动时间偏长),并且有时还会自动熄火,同时发动机故障灯点亮。该车
五味子叶中含有多糖、木脂素、黄酮和微量元素等有效成分。试验对五味子叶多糖进行分析提纯,构建五味子叶中多糖与小分子氨基酸(赖氨酸和甘氨酸)通过美拉德反应形成共聚物,以
党的十八届三中全会对做好新形势下的党风廉政建设和反腐败工作做出了重要部署,提出了“强化各级党委抓党风廉政建设的主体责任”的工作要求。作为基层党组织,深化认识全面深
Background-Sirolimus-eluting stents(SESs)reduce angiographic restenosis in patients with focal, native coronary artery stenoses. This study evaluated the useful
彩色多普勒血流显像(CDFI)在诊断股动脉假性动脉瘤中的作用和价值已得到临床的广泛认可和肯定。但CD FI对股动脉假性动脉瘤的治疗作用目前报道较少。本研究应用A U4彩色多普
2013年11月,中共中央和国务院印发了《党政机关厉行节约反对浪费条例》(以下简称《条例》),并发出通知,要求各地区各部门认真贯彻执行。《条例》分总则、经费管理、国内差旅
当前,正在开展的党的群众路线教育实践活动,是以习近平同志为总书记的新一届中央领导集体,在全党领导的一场深刻的党内风气变革。省委书记王宪魁指出,开展党的群众路线教育实
沱江河依着凤凰的城墙缓缓流淌,世世代代哺育着古城儿女。坐上乌船,听着艄公的号子,看着两岸已有百年历史的土家吊脚楼,别有一番韵味。沱江的河面并不宽,但它却是凤凰古城一
本刊讯(通讯员/程淑红)近日,石台县荣获“全国休闲农业与乡村旅游示范县”荣誉称号,再添一块国字号奖牌。近年来,石台县委、县政府把发展休闲农业和乡村旅游作为农民增收和拉