麒麟类可可脂(Kylinfat简称K脂)是用乌梅果实皮脂制备的类可可脂,用于替代可可脂生产巧克力。本测试选用昆明小鼠30只,分5组,实验组分高、中、低3个剂量组,每天分别给予K脂(加热液化后)10、5和1mg/kg体重,阴性对照组每天给5ml/kg体重花生油,阳性对照组每天给予50mg/kg体重环磷酰胺,各组均连续3d灌胃。末次灌胃后6h处死动物取股骨,按常规方法测得各实验组骨髓嗜多染红细胞微核率分别为1.5‰、1.67‰和2。 Kylinfat (Kylinfat) is a type of cocoa butter prepared from the sebum of ebony fruit used as a substitute for cocoa butter to produce chocolate. In this test, 30 Kunming mice were selected and divided into 5 groups. The experimental groups consisted of high, medium and low dose groups. Each day was given K fat (after heating and liquefaction) at 10, 5 and 1 mg/kg body weight. The negative control group was given daily. 5ml/kg body weight of peanut oil, positive control group was given cyclophosphamide 50mg/kg body weight every day, each group were given intragastric administration for 3 days. The femurs were sacrificed 6 hours after the last gavage, and the micronucleus rate of bone marrow polychromatic erythrocytes in each experimental group was determined to be 1.5 ‰, 1.67 ‰, and 2 by conventional methods.