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近20年来,社区相关性耐甲氧西林金黄色葡萄球菌(CA-MRSA)感染病例报道不断增多,CA-MRSA缺乏诸多医院相关危险因素,并具有特殊的耐药性特征,且具有特异的毒力因子(PVL)和染色体基因型。临床表现以皮肤软组织感染(SSTI)为主,部分严重小儿病例可进展为脓毒血症而危及生命。该文就有关CA-MRSA的定义、流行状况和特征、鉴定方法及临床特征等研究现状作一综述。
Over the past 20 years, there have been reports of a growing number of community-related infections with methicillin-resistant Staphylococcus aureus (CA-MRSA). CA-MRSA lacks many hospital-related risk factors and has special drug resistance characteristics and has a specific toxicity Force Factor (PVL) and Chromosomal Genotypes. Clinical manifestations of skin and soft tissue infections (SSTI), some serious cases of children can progress to sepsis and life-threatening. This article reviews the current status of research on the definition, prevalence and characteristics of CA-MRSA, identification methods and clinical features.