尽管许多研究文献已经证明,在乙型肝炎病毒(以下简称HBV)感染者和慢性肝病患者中普遍存在乙肝表面抗原(以下简称HBsAg)阳性状况,但从两者观察的资料情况来看,HBsAg(-)HBV感染的流行情况和临床意义不是很清楚。在HBsAg(-)HBV感染病例中,为什么HBV复制很不明显,许多研究设法解释 Although many studies have shown that hepatitis B surface antigen (hereinafter referred to as HBsAg) prevalence in hepatitis B virus (hereinafter referred to as HBV) and chronic liver disease prevalence, but the information observed from both the situation, HBsAg ( -) The prevalence and clinical significance of HBV infection is not well understood. In the case of HBsAg (-) HBV infection, why HBV replication is not obvious, many studies try to explain