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穿心莲Andrographis paniculata Nees系爵床科须药草属一年生草本植物。已报导所含二萜内酯成分有穿心莲内酯(Andrographolide)、新穿心莲内酯(Neo-andrographolide)、脱氧穿心莲内酯(Deoxy-andrographolide),脱水穿心莲内酯(14-deoxy-11-dehydro-andrographolide)和氧代穿心莲内酯(14-deoxy-11-oxaandrograph-olide)五种。今作者从穿心莲中分离到一种新二萜内酯甙(晶23号)。本品为白色簇状结晶,熔点187～188℃,〔α〕_D~(35)-30 (C=1,无水乙醇)。薄层层析,采用硅胶CMC-Na板,氯仿-甲醇(8∶2)展开,kedde试剂显色RfO.31。味极苦,溶于
Andrographis paniculata Nees Andrographis paniculata Nees is an annual herb. It has been reported that the diterpene lactones contained Andrographolide, Neo-andrographolide, Deoxy-andrographolide, Dehydroandrographolide (14-deoxy-11-dehydro- Andrographolide) and oxo-andrographolide (14-deoxy-11-oxaandrograph-olide). The present author isolated a new diterpene lactone (Crystal No. 23) from Andrographis paniculata. This product is a white cluster crystal, melting point 187 ~ 188 °C, [α] _ D ~ (35) -30 (C = 1, anhydrous ethanol). TLC, silica gel CMC-Na plate, chloroform-methanol (8:2) developed, kedde reagent color RfO.31. Extremely bitter, soluble