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255例不同时期脑血管病惠者,急性脑梗塞惠者101例,男55例,女46例,平均年龄59.67±10.42岁;高血压脑出血43例,男31例,女12例,平均年龄60.44±7.93岁;恢复期脑梗塞患者28例,男17例,女11例,平均年龄59.26±6.49岁;脑动脉硬化惠者83例,男46例,女37例,平均年龄56.44±5.37岁。对其血清中的高密度脂蛋白胆固醇(HDL-C)及亚组分进行了测定。结果发现,脑动脉硬化组、急性脑梗塞组、高血压脑出血组、恢复期脑梗塞组患者血清中的HDL-C 及HDL-2C 均较正常对照组明显降低(P<0.001),HDL-3C则变化不大。而不同时期脑血管病患者的低密度脂蛋白(LDL-C)较正常对照组明显升高。作者认为HDL-C 尤其是HDL-2C 的下降或许是发生脑血管病的危险因素。
There were 101 cases of acute cerebral infarction benefited from 255 cases of acute cerebral infarction, including 55 males and 46 females, with an average age of 59.67 ± 10.42 years. Hypertensive intracerebral hemorrhage was performed in 43 cases, 31 males and 12 females, with an average age of 60.44 ± 7.93 years; recovery of cerebral infarction in 28 patients, 17 males and 11 females, mean age 59.26 ± 6.49 years; 83 cases of cerebral arteriosclerosis beneficiaries, 46 males and 37 females, mean age 56.44 ± 5.37 years . Serum HDL-C and its sub-components were measured. The results showed that serum HDL-C and HDL-2C levels in patients with cerebral arteriosclerosis, acute cerebral infarction, hypertensive intracerebral hemorrhage and convalescent cerebral infarction were significantly lower than those in normal control (P <0.001) 3C is not much change. The levels of LDL-C in patients with cerebrovascular disease at different stages were significantly higher than those in normal controls. The authors conclude that a decrease in HDL-C, especially HDL-2C, may be a risk factor for developing cerebrovascular disease.