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目的研究睡眠呼吸暂停综合征（ＳＡＳ）对脑血流及其脑功能的影响。方法选择年龄、性别和基础疾病相配对的老年患者，ＳＡＳ组３０例，对照组３２例。ＳＡＳ经多导睡眠监测仪检查而诊断。用阿克松多功能彩超仪检测双侧大脑前、中、后动脉的血流速度和频谱形态。结果ＳＡＳ组与对照组的收缩期血流峰值（Ｖｓ）、舒张期血流峰值（Ｖｄ）、平均血流速度（Ｖｍ）、阻力指数（ＲＩ）等９项指标均有显著差异（Ｐ＜０．０５～Ｐ＜０．０１），ＳＡＳ组血流频谱形态异常增多。结论ＳＡＳ患者脑血流速度减慢，频谱形态异常增多，提示ＳＡＳ可促发脑供血不足、脑动脉硬化，易导致缺血性脑卒中等脑血管疾病的发生
Objective To study the effects of sleep apnea syndrome (SAS) on cerebral blood flow and brain function. Methods 30 elderly patients with matched age, gender and underlying diseases were selected as SAS group and 32 as control group. SAS is diagnosed by polysomnography. Akerson multi-function color Doppler was used to measure the blood flow velocity and spectral shape of bilateral anterior, middle and posterior arteries. Results There were significant differences among the 9 indexes in systolic (SAS) group and control group (Vs), peak diastolic blood flow (Vd), mean blood flow velocity (Vm) and resistance index .05 ~ P <0.01), SAS group blood flow spectrum abnormalities increased. Conclusions SAS has a slowed cerebral blood flow velocity and abnormally increased frequency spectrum. It suggests that SAS can induce cerebral insufficiency, cerebral arteriosclerosis and easily cause cerebrovascular diseases such as ischemic stroke.