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目的 :探讨颈动脉粥样硬化的临床意义及与颈内动脉系统TIA预后的关系。方法 :采用彩色多普勒超声对 5 3例TIA患者颈动脉进行检测 ,并随访 12个月 ,比较TIA复发、发展为脑梗死与无复发TIA患者颈动脉粥样硬化的特征。结果 :5 3例TIA患者在随访期间有TIA复发 18例 ,发展为脑梗死 19例 ,颈动脉粥样硬化的TIA复发率明显高于无颈动脉粥样硬化的TIA。颈动脉狭窄 12例TIA复发 3例 ,发展为脑梗死 9例 ;斑块 14例 ,TIA复发 6例 ,发展为脑梗死 6例 ;内膜增厚 13例 ,TIA复发 6例 ,发展为脑梗死 3例 ,其复发率明显高于无颈动脉粥样硬化患者 ,经Radit分析发现颈动脉粥样硬化的严重程度与TIA的预后成正相关。结论 :颈动脉粥样硬化与颈动脉系统TIA的预后密切相关 ,颈动脉粥样硬化的严重程度是颈动脉系统TIA的危险因素 ,可作为颈动脉系统TIA预后指标。
Objective: To investigate the clinical significance of carotid atherosclerosis and the relationship with the prognosis of internal carotid artery TIA. Methods: The carotid arteries of 53 patients with TIA were examined by color Doppler sonography and followed up for 12 months. The recurrence of TIA was compared with that of carotid atherosclerosis in patients with cerebral infarction and non-recurrent TIA. Results Totally 53 cases of TIA patients had TIA recurrence in 18 cases and 19 cases of cerebral infarction. The recurrence rate of carotid atherosclerosis TIA was significantly higher than that of carotid atherosclerosis TIA. Carotid stenosis in 12 cases of TIA recurrence in 3 cases, the development of cerebral infarction in 9 cases; plaque in 14 cases, TIA recurrence in 6 cases, the development of cerebral infarction in 6 cases; intimal thickening in 13 cases, TIA recurrence in 6 cases, the development of cerebral infarction 3 cases, the recurrence rate was significantly higher than those without carotid atherosclerosis, by Radit analysis found that the severity of carotid atherosclerosis and TIA was positively correlated with the prognosis. Conclusion: Carotid atherosclerosis is closely related to the prognosis of TIA in carotid system. The severity of carotid atherosclerosis is a risk factor of TIA in carotid system and can be used as a prognostic indicator of TIA in carotid system.