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病毒性乙型肝炎(以下简称乙肝)是严重危害人民健康的疾病之一,寻求其免疫预防办法是人们长期奋斗的目标。1986年4月~1987年5月,在西安市郊区,以5~9岁儿童为研究对象,进行随机、双盲和有安慰剂对照的现场实验,对国产血源性乙肝疫苗效果进行评价。本文就疫苗的安全性和近期效果总结于后。1 对象与方法1.1 1986年4月,先对5~9岁学前班和
Viral hepatitis B (hereinafter referred to as hepatitis B) is one of the diseases that seriously endanger people’s health. To seek its immunoprophylaxis is the long-term goal of people. From April 1986 to May 1987, a randomized, double-blind and placebo-controlled field trial was conducted in suburbs of Xi’an City to study the effects of domestic Hepatitis B vaccine on children aged 5 to 9 years. This article summarizes the safety and recent efficacy of the vaccine. 1 objects and methods 1.1 April 1986, first of 5 to 9 years of age and pre-school classes