唾液亚硝酸盐约占体内总量的80％,其含量受多种因素的影响,如食物、药物、吸烟、空气污染及口腔细菌等,并对体内致癌性亚硝胺的形成有重要作用。大量证据表明,亚硝胺与食管癌的形成有关。据此,我们对林县食管癌高发区人群口腔卫生、吸烟状况及冬季室内空气中氮氧化物与唾液亚硝酸盐的关系作了调查。 Saliva nitrite accounts for about 80% of the total amount in the body, its content is affected by many factors, such as food, medicine, smoking, air pollution and oral bacteria, and the formation of carcinogenic nitrosamines in vivo play an important role. Numerous evidences indicate that nitrosamines are associated with the formation of esophageal cancer. Based on this, we investigated the oral hygiene and smoking status of people with high incidence of esophageal cancer in Linxian County and the relationship between nitrogen oxides and saliva nitrite in winter indoor air.