[目的]寻找符合老龄肺结核的合理化疗方案。[方法]回顾性分析1996—2004年在泉州市疾控中心就诊初治涂阴的78例老龄肺结核患者的临床表现、病灶范围及治疗结果。[结果]患者均用6 HRE(即:异烟肼、利福平和乙胺丁醇,全程6个月)治疗,取得满意疗效者占97.4%(76/78)。[结论]初治涂阴的老龄肺结核患者,结核中毒症状较轻、病灶分布1~3个肺野或相当于3个肺野、无结核空洞的者用6HRE方案治疗,可取得满意效果。 [Objective] To find a reasonable chemotherapy regimen for elderly pulmonary tuberculosis. [Methods] A retrospective analysis of clinical manifestations, extent of lesions and treatment outcome of 78 elderly patients with pulmonary tuberculosis who were initially smear-negative at the CDC of Quanzhou from 1996 to 2004 was retrospectively analyzed. [Results] All patients were treated with 6 HRE (isoniazid, rifampin and ethambutol for 6 months), and 97.4% (76/78) achieved satisfactory results. [Conclusion] The initial treatment of old pulmonary tuberculosis patients with tuberculosis, mild symptoms of tuberculosis, lesions distribution of 1 to 3 lung fields or equivalent to 3 lung field, no tuberculosis holes were treated with 6HRE program, satisfactory results can be obtained.