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目的探讨PCR在骨与关节结核诊断中的应用价值。方法选取2015年1月—2017年3月该院收治的49例骨与关节结核患者的临床资料为研究对象,分别应用PCR检测方法和抗酸检测法对其关节积液结核杆菌进行检测,并观察两种检测方法的阳性率及假阴性率情况。结果 PCR检测方法在阳性率、假阴性率等方面均显著优于抗酸法,两种方法的比较差异有统计学意义(P<0.001)。结论 PCR在骨与关节结核的早期诊断中应用效果显著,可靠性强,具有临床推广价值。
Objective To explore the value of PCR in the diagnosis of bone and joint tuberculosis. Methods The clinical data of 49 patients with bone and joint tuberculosis admitted from January 2015 to March 2017 in our hospital were selected for the study. PCR and anti-acid test were used to detect the Mycobacterium tuberculosis of the joint effusion Observe the positive rate and false negative rate of the two methods. Results PCR detection method was significantly better than antacid method in the positive rate, false negative rate and other aspects, the difference between the two methods was statistically significant (P <0.001). Conclusion PCR in the early diagnosis of bone and joint tuberculosis effect is significant, reliable, with clinical value.