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甲型(HAV),乙型(HBV)与非甲非乙型(NANB)肝炎病毒感染所引起的病毒性肝炎(VH)是一种以肝脏损害为主的全身性疾病。其暴发型(暴肝)是造成85％以上暴发性肝脏功能衰竭(暴肝功衰)的病原学因素。其中HBV暴肝(暴乙肝)约占42～59％。我国VH发病率较高,暴肝也比较多见,女性多于男性,且多见于孕妇。国内外统计暴肝的死亡率迄今仍为80～90％。本病是肝脏遭受病毒感染后,由多种因素与机制造成大面积肝细胞急剧坏死的结果。其决定因素究竟是肝细胞坏死的广泛性与急剧性,还是肝细胞再生机能衰竭之故,迄今虽无定论,但病毒感染后所诱发的肝微循环障碍导致肝实质细胞缺血缺氧,可以说就是肝
Viral hepatitis (VH) caused by hepatitis A virus (HAV), hepatitis B virus (HBV) and non-B hepatitis virus (NANB) is a systemic disease characterized mainly by liver damage. Its outbreak (stubborn liver) is caused by more than 85% of fulminant liver failure (liver failure) etiological factor. Of which HBV stubborn liver (violent hepatitis B) accounts for about 42 ~ 59%. The incidence of VH in our country is higher, storms liver is also more common, more women than men, and more common in pregnant women. Statistics at home and abroad the death rate of liver cirrhosis is still 80 to 90%. The disease is the result of a large number of liver cells necrosis caused by a variety of factors and mechanisms after the liver is infected with the virus. The deciding factor is whether hepatocellular necrosis is widespread and rapid, or the failure of liver cell regeneration, so far, though inconclusive, but the liver microcirculation disorder induced by virus infection leads to hepatic parenchymal ischemia and hypoxia, can That is the liver