白细胞介素2通过与其特异性细胞表面受体(又称Tac抗原)相互作用而诱导T细胞增殖.T淋巴细胞表达IL2受体需要一定的信号.T细胞的抗原特异性受体的单克隆抗体和T细胞表面蛋白(如人类T_3分子)的单克隆抗体便是这样的信号.pHA和ConA也具有这种作用.本文用高度提纯的正常供血者的外周血T细胞以及纯化的天然IL2和重组IL2进行实验,探讨了T细胞表达IL2受体及增殖所需的条件.作者用适宜剂量的PHA刺激T细胞,将细胞培养3天后用抗Tac抗体作荧光活化细 Interleukin 2 induces proliferation of T cells by interacting with its specific cell surface receptor, also known as Tac antigen, which requires some signal for the expression of IL2 receptors by T lymphocytes Monoclonal antibodies to antigen-specific receptors of T cells And T cell surface proteins (such as human T 3 molecules) monoclonal antibody is such a signal.pHA and ConA also have this effect.In this paper, with highly purified normal donor peripheral blood T cells and purified native IL2 and recombinant IL2 to explore the conditions required for T cells to express IL2 receptor and to proliferate.The authors stimulated T cells with appropriate dose of PHA and cultured the cells for 3 days with anti-Tac antibody for fluorescence activation