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目的 :观察大承气汤冲剂术后早期使用促进肠功能早期恢复 ,提高围手术期治疗效果的作用。 方法 :选择上腹部手术病人 10 0例 ,随机分为中药组和对照组。中药组在术后 1～ 3d给予大承气汤冲剂 ,从术后肠音恢复时间、排气、排便和进食时间、肺通气功能和血氧饱和度变化、血浆内毒素及胃动素变化等指标进行了观察。 结果 :术后早期在没有禁忌症条件下 ,服用大承气汤冲剂 ,使进食和排便时间提前 ,加快术后的恢复 ,同时肺功能SaO2 和FEV1 0 (%PRED)也得到改善 ,促进血浆内毒素水平早期下降及胃动素水平提高等。 结论 :术后早期使用大承气汤冲剂具有提高围手术期治疗效果 ,预防肠源性感染的作用
Objective: To observe the early use of Dachengqitang Granules for early recovery of intestinal function and improve the effect of perioperative treatment. Methods: One hundred and ten patients with upper abdominal surgery were randomly divided into traditional Chinese medicine group and control group. The Chinese medicine group was given Dachengqi Decoction 1 to 3 days after operation, from the recovery time of postoperative bowel sounds, degassing, defecation and feeding time, pulmonary ventilation function and oxygen saturation, changes in plasma endotoxin and motilin, etc. Indicators were observed. RESULTS: In the early postoperative period, Dachengqitang Granules were taken without contraindications to advance the time of eating and defecation and to accelerate postoperative recovery. At the same time, pulmonary function SaO2 and FEV1 0 (%PRED) were also improved and promoted in the plasma. Early toxin levels decreased and motilin levels increased. Conclusion : Early use of Dachengqi Decoction can improve the effect of perioperative treatment and prevent intestinal infection