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目的观察左氧氟沙星与加替沙星对慢性支气管炎急性发作的疗效,为临床应用提供理论依据。方法 112例慢性支气管炎急性发作患者随机分为治疗组和对照组,每组56例。治疗组给予左氧氟沙星注射液(0.4),1次/d,连用10d,盐酸氨溴索葡萄糖注射液(30mg:100ml)2次/d,连用5d。对照组应用加替沙星注射液(0.4g),1次/d,连用10d,盐酸氨溴索葡萄糖注射液(30mg:100ml)2次/d,连用5d。结果治疗组临床缓解率82%,为显著改善。对照组临床缓解率55%,为一般改善。结论左氧氟沙星治疗慢性支气管炎急性发作的疗效优于加替沙星。
Objective To observe the curative effect of levofloxacin and gatifloxacin on acute exacerbation of chronic bronchitis, and to provide a theoretical basis for clinical application. Methods 112 cases of acute exacerbation of chronic bronchitis were randomly divided into treatment group and control group, 56 cases in each group. The treatment group was given levofloxacin injection (0.4) once a day for 10 days, followed by ambroxol hydrochloride glucose injection (30mg: 100ml) twice daily for 5 days. The control group was given Gatifloxacin injection (0.4g) once a day for 10 days, followed by ambroxol hydrochloride glucose injection (30mg: 100ml) twice daily for 5 days. Results The clinical response rate of the treatment group was 82%, which was significantly improved. The control group clinical remission rate of 55%, as a general improvement. Conclusion The efficacy of levofloxacin in the treatment of acute exacerbation of chronic bronchitis is superior to gatifloxacin.