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目的：总结纵隔淋巴结转移（N2）肺癌的外科治疗效果，探讨其临床病理特点与预后关系。方法：用SPSS软件对我院外科治疗1083例非小细胞肺癌建立数据库，对其中147例N2肺癌进行统计分析。结果：N2组中鳞癌发生率最低，肺鳞癌淋巴结转移度明显低于其他类型肺癌（P＜0．01），其预后明显优于肺腺癌（P＜0．05）。根治性切除者淋巴结转移度明显低于姑息性切除者，预后明显优于姑息性切除者（P＜0．05）。淋巴结转移数与预后有关，＞4枚者预后差（P＜0．05）。手术方式及术后综合治疗与预后无明显关系。结论：肺癌外科治疗常规进行纵隔淋巴结清扫对达到根治效果和准确分期十分必要。
Objective: To summarize the surgical treatment effect of mediastinal lymph node metastasis (N2) lung cancer, and to explore the relationship between its clinicopathological features and prognosis. METHODS: A database of 1,083 patients with non-small cell lung cancer was surgically treated with SPSS software. 147 N2 lung cancers were statistically analyzed. Results: The incidence of squamous cell carcinoma was the lowest in N2 group. The lymph node metastasis of lung squamous cell carcinoma was significantly lower than that of other types of lung cancer (P<0.01). The prognosis was significantly better than that of lung adenocarcinoma (P<0.05). The degree of lymph node metastasis in radical resection was significantly lower than that in palliative resection, and the prognosis was significantly better than that in palliative resection (P<0.05). The number of lymph node metastasis was related to the prognosis, and the prognosis was poor in >4 individuals (P<0.05). Surgical methods and postoperative comprehensive treatment have no significant relationship with prognosis. Conclusion: The routine surgical treatment of lung cancer for mediastinal lymph node dissection is essential to achieve a radical effect and accurate staging.