加拿大卡尔加里大学的研究人员发现,通常引起轻微呼吸道感染的呼肠孤病毒能选择性攻击癌细胞,而不破坏正常细胞.呼肠孤病毒用于复制的系统依赖于一组基因(包括ras致癌基因),它们在许多癌症中亦可被激活.该基因组称为ras通道,可调节细胞生长,并且在50%以上的癌症(包括乳腺癌、胰腺癌和脑癌)中过度活跃.研究人员曾证实,当ras基因激活时,通常能抵抗呼肠孤病毒感染的细胞会成为易感细胞. Researchers at the University of Calgary in Canada have found that reoviruses that usually cause mild respiratory infections can selectively attack cancer cells without destroying normal cells. The system that reovirus uses for replication depends on a group of genes (including ras cancer Genes), which can also be activated in many cancers. The genome is called ras channel, regulates cell growth, and is overactive in more than 50% of cancers (including breast, pancreatic, and brain cancers). It was confirmed that when the ras gene is activated, cells that are generally resistant to reovirus infection become susceptible cells.