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目的 探讨口腔软组织肉瘤的生物学特性及其治疗效果。方法 以该院收治的35 例口腔软组织肉瘤为分析对象,进行疗效分析。结果 本组35 例的3 a 和5 a 生存率分别是31-4% 和20-0% ;局部复发率为40-0 % ,远处转移率为42-9% 。结论 口腔软组织肉瘤是恶性度较高的头颈部恶性肿瘤,有较高的局部复发率和远处转移率,疗效较差;本病的治疗以手术治疗为主,应坚持广泛切除术的原则,手术安全切缘至少要有3cm ;术后放疗可降低局部复发率及远处转移率;辅助性化疗对提高疗效有帮助。
Objective To investigate the biological characteristics of oral soft tissue sarcoma and its therapeutic effect. Methods 35 cases of oral soft tissue sarcoma treated in our hospital were analyzed, and the curative effect was analyzed. Results The survival rates at 3 years and 5 years in 35 cases were 31-4% and 20-0% respectively. The local recurrence rate was 40-0% and the distant metastasis rate was 42-9%. Conclusion Oral soft tissue sarcoma is a highly malignant head and neck malignant tumor with high local recurrence rate and distant metastasis rate with poor curative effect. The treatment of this disease is mainly based on surgical treatment, and the principle of extensive excision should be adhered to , Surgical margin of at least 3cm safety; postoperative radiotherapy can reduce the local recurrence rate and distant metastasis; adjuvant chemotherapy to improve the efficacy of help.