人类口腔中定植的细菌有700余种,它们之间的相互关系与口腔疾病的发生、发展存在着密切的生态学联系。牙周病和龋病是人类常见的由口腔常驻细菌引起的细菌感染性疾病。牙周病是宿主的龈下正常微生物动态平衡被破坏,导致牙周袋的发生和牙槽骨的破坏等[1]。龋病是由某些链球菌和 There are more than 700 kinds of bacteria colonized in human oral cavity, and the correlation between them is closely related to the occurrence and development of oral diseases. Periodontal disease and caries are common bacterial infections caused by bacteria resident in the mouth. Periodontal disease is the host of subgingival normal microorganisms dynamic balance is destroyed, resulting in the occurrence of periodontal pocket and alveolar bone destruction [1]. Caries are caused by certain streptococci and