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生大黄可减轻酒精对家兔的肝脏炎症和坏死作用，可显著减少病员粪便中厌氧菌与需氧菌的菌落数。生大黄等综合治疗组的肝性昏迷清醒率为82．5％，明显高于对照组47.85％，P＜0.001，而清醒时间（1．01±0．96）也显著短于对照组（1．86±1．35），P＜0．01。提示生大黄可作为肝硬化患者发生肝性昏迷的综合治疗方法之一。
Rhubarb can reduce the effects of alcohol on rabbit liver inflammation and necrosis, and can significantly reduce the number of anaerobic and aerobic bacteria colonies in the stool of patients. The recovery rate of hepatic coma in the combined treatment group such as rhubarb was 82.5%, which was significantly higher than that of the control group (47.85%, P<0.001), and the time of awakening (1.01±0.96) was also significantly shorter than that of the control group (1 .86±1.35), P<0.01. Tip rhubarb can be used as a comprehensive treatment of hepatic coma in patients with liver cirrhosis.