用放射性同位素或生物素标记的单核苷酸,可以标记DNA,制备基因探针,用于检测同源DNA和mRNA。基因探针已广泛地应用于分子生物学研究,也用于遗传和感染性疾病的诊断。由于使用基因探针进行检测,具有高度敏感性和特异性,近年来进展很快。在开展嗜肝DNA病毒同肝癌相关关系的分子生物学研究中,我们采用国产核酸工 Using radioactive isotopes or biotinylated single nucleotides, DNA can be labeled and gene probes can be prepared for the detection of homologous DNA and mRNA. Gene probes have been widely used in molecular biology research, but also for the diagnosis of genetic and infectious diseases. Due to the high sensitivity and specificity of using gene probes for detection, progress has been made rapidly in recent years. In the study of molecular biology of hepatotoxicity associated with hepatocarcinoma with hepatocellular carcinoma, we used domestic nucleic acid