非酒精性脂肪性肝病(NAFLD)是指除外酒精和其他明确的肝损害因素所致、以弥漫性肝细胞大泡性脂肪变为主要特征的临床病理综合征,与肥胖、2型糖尿病、血脂异常等伴随的胰岛素抵抗(IR)关系密切。常见胰岛素增敏剂是否能改善NAFLD,目前尚无定论,常见胰岛素增敏剂噻唑烷酮类(TZDs)用于NAFLD是否优于二甲双胍(MF)目前也尚无定论,本文就胰岛素增敏剂与NAFLD相关 Non-alcoholic fatty liver disease (NAFLD) refers to the addition of alcohol and other specific liver damage caused by factors that diffuse hepatocytic bullous steatosis as the main feature of clinical and pathological syndrome, and obesity, type 2 diabetes, blood lipids Abnormalities and other accompanying insulin resistance (IR) are closely related. Whether common insulin sensitizers can improve NAFLD is still inconclusive. It is still inconclusive whether common insulin sensitizers thiazolidinones (TZDs) are superior to metformin (NAFLD) for NAFLD. In this paper, NAFLD related