基于神经影像精准定位颅内病变体表投影方法的临床应用效果分析

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目的:探讨一种基于神经影像学及体表标志的简易计算方法在定位颅内病变体表投影中的应用价值。方法:回顾性分析厦门大学附属第一医院神经外科2021年1—6月收治的46例使用基于神经影像学及体表标志的简易计算方法——双圆法,进行基准点识别的颅内占位患者的临床资料。男性29例,女性17例,年龄(48.2±10.6)岁(范围:28~72岁)。术前患者头部随机贴附2枚电极片(人工基准点)后行颅脑薄层CT检查,并根据影像学检查图像分别测量各基准点到鼻根和同侧耳屏的直线距离。在患者头部,使用圆规分别以鼻根和同侧耳屏为圆心,以测量的距离为半径在基准点附近绘制弧线,两弧线在头皮表面的交点即为基准点。两名神经外科医师按照“双圆法”进行基准点识别,分别记录测量时间和识别结果与实际基准点的误差距离。数据比较采用独立样本t检验,组间一致性分析采用Kappa检验。结果:46例患者共采集基准点92个,第1名医师测量每例患者的时间为(8.1±2.3)min(范围:5~15 min),第2名医师为(8.9±3.5)min(范围:4~17 min);第1名医师经“双圆法”定位与实际基准点的误差距离为(4.4±2.4)mm(范围:0~12 mm),第2名医师的定位误差距离为(4.2±2.6)mm(范围:0~14 mm)(n t=-0.575,n P=0.567),差异无统计学意义。两名医师定位误差的一致性检验结果显示,一致性中等(Kappa=0.517,n P=0.001)。其中8例患者分别在“双圆法”和神经导航下进行病变投影位置定位,患者病变直径为(3.8±0.9)cm(范围:2.6~5.1 cm),双圆法定位与导航定位误差为(4.0±1.9)mm(范围:1~6 mm),且所有患者术中均证实定位准确。n 结论:“双圆法”在定位颅内病变体表投影中简单方便、快速准确,可作为一种简便的定位方法。“,”Objective:To explore the feasibility of a method based on nearoimaging and surface markers for locating scalp projection of intracranial lesions.Methods:The clinical data of 46 patients who were used\'double-circle method ′ for locating scalp projection of intracranial lesions at Department of Neurosurgery,the First Affiliated Hospital of Xiamen University from January to June 2021 were retrospective analyzed. All patients with 2 electrodes(artificial fiducials) randomly attached to scalp had been examed thin-layer brain CT. The distances from the center of each fiducial to the root of the nose and tragus were measured through the images. A compass was used to draw two arcs with the root of nose and the tragus as the center and the pre-measured distance as the radius on patient′s scalp. Then two arcs′ intersection on the scalp is the fiducial. The method is named′ double-circle method′. Two neurosurgeons were arranged to perform fiducial identification with double-circle method, and record the error between the result and the actual fiducial point.Independent sample n t test was used for data comparison, and Kappa test was used to analysis the inter-group consistency.n Results:Ninety-two fiducial points of 46 patients were collected. Time consuming of doctor A was (8.1±2.3) minutes(range:5 to 15 minutes)and doctor B was (8.9±3.5) minutes(range:4 to 17 minutes).The positioning error from the doctor A was (4.4±2.4)mm(range:0 to 12 mm) and doctor B was(4.2±2.6) mm(range:0 to 14 mm)(n t=-0.575,n P=0.567),the difference was not statistically significant. The Kappa value of the consistency test of error between two doctors was 0.517(n P=0.001).The consistency was moderate.Eight patients used′ double-circle method′ and neuronavigation for locating scalp projection of intracranial lesions at the same time. The diameter of the lesions was (3.8±0.9)cm (range: 2.6 to 5.1 cm), and the positioning error of the′ double-circle method′ and navigation was (4.0±1.9) mm(range: 1 to 6 mm), and all patients were confirmed to be accurately located during surgery.n Conclusion:Double-circle method is a simple,convenient and accurate way in locating intracranial lesions and has certain clinical significance.
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