该文对银杏内酯A ,B和白果内酯的定性定量分析方法进行研究 .用 2 0 %的甲醇水溶液提取银杏叶中的银杏内酯A ,B和白果内酯 ,用硅胶柱纯化 ,甲苯与丙酮混合液洗脱 ,经硅烷化后质谱定性 ,气相色谱定量 .该方法对白果内酯与银杏内酯A ,B的回收率分别为 93.0 1% ,96 .32 % ,94.6 8% ,相对变异系数分别为 5 75 % ,3 88% ,4 2 3% In this paper, the qualitative and quantitative methods of ginkgolide A, B and bilobalide were studied.The Ginkgolide A, B and bilobalide in Ginkgo biloba leaves were extracted with 20% methanol aqueous solution and purified by silica gel column with toluene And acetone, the mass spectrum was quantified by silylation and the gas chromatographic method.The recoveries of bilobalide and ginkolide A and B were 93.0 1%, 96.32% and 94.6 8% The coefficients of variation were 5 75%, 3 88%, 42 23%