血红蛋白H病(HbH)属遗传性溶血性贫血,是α地中海贫血的一种类型。作者于1978～1980年用牌切除术治疗HbH患者19例。手术后均有症状减轻,Hb由5.6g升至8.6g,达到8 g以上者占73.3％,红细胞寿命由14.3天升至19.2天.术后Hb增加水平与术前Hb水平呈负相关。根据本组患者术前Hb水平和术后增长的克数提出了预测脾切除后Hb上升值=7.53_4 Hemoglobin H disease (HbH) is a hereditary hemolytic anemia, which is a type of alpha thalassemia. The author in 1919-1980 using brand resection of HbH patients in 19 cases. Symptoms were relieved after operation, Hb increased from 5.6g to 8.6g, 73.3% of patients with more than 8 g, life span of erythrocytes increased from 14.3 days to 19.2 days, and the postoperative Hb level was negatively correlated with preoperative Hb level. According to this group of patients preoperative Hb level and the number of grams of postoperative increase in the prediction of Hb rise after splenectomy = 7.53_4