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目的:了解海南省育龄妇女乙肝表面抗原(HBsAg)携带情况,为制定乙肝干预策略提供参考依据。方法:采用多阶段分层整群抽样方法于2007年11月～2008年12月在海南省18个市县抽取36个乡镇、72个村庄共1 0000名15～49岁育龄妇女进行HBsAg携带情况调查,采用ELISA法进行HBsAg检测。结果:合格样本9493例,育龄妇女HBsAg总携带率9.56%,不同年龄、民族、地区育龄妇女携带率差异均有统计学意义(P<0.05)。20～29岁携带率最高(10.49%),黎族(10.28%)>汉族(9.09%)>其他少数民族(6.29%);携带率高于10.00%的市县有9个,白沙县(15.03%)最高,三亚市(2.03%)最低。结论:海南省育龄妇女HBsAg携带率处于偏高水平,因此相关部门应加强育龄妇女的HBsAg筛查,开展预防乙肝的健康教育,以进一步控制和减少育龄妇女HBsAg携带率。
Objective: To understand the situation of hepatitis B surface antigen (HBsAg) carried by women of childbearing age in Hainan Province, and to provide a reference for the development of hepatitis B intervention strategy. Methods: From November 2007 to December 2008, 36 villages and townships and 36 villages and towns in 72 villages were enrolled in this study. A total of 1 0000 women of childbearing age from 15 to 49 were enrolled in this study from November 2007 to December 2008. Investigation, using HBsAg ELISA test. Results: A total of 9493 eligible samples were obtained. The total carrying rate of HBsAg in women of childbearing age was 9.56%. The carrying rates of women of childbearing age in different age groups, ethnic groups and regions were all significantly different (P <0.05). (10.29%), Han (9.09%)> other ethnic minorities (6.29%); 9 cities and counties with carrying rate higher than 10.00%, Baisha County (15.03% ) Highest, Sanya (2.03%) the lowest. Conclusion: The rate of carrying HBsAg among women of childbearing age in Hainan Province is at a high level. Therefore, relevant departments should strengthen the screening of HBsAg among women of childbearing age and carry out health education on prevention of hepatitis B so as to further control and reduce the HBsAg carrier rate among women of childbearing age.