整合素是一类重要的细胞表面受体, 主要介导细胞 细胞外基质(ECM)之间的相互作用, 参与生物体内多种生理和病理过程, 如器官发生、基因表达的调节、细胞增殖、分化、移行、死亡等。此外, 整合素在心脏的发育、生长及对病理生理信号产生反应的过程中也具有重要的作用。心血 Integrins are important cell surface receptors that mainly mediate the interaction between extracellular matrix (ECM) cells and participate in various physiological and pathological processes in organisms, such as organogenesis, gene expression regulation, cell proliferation, Differentiation, migration, death and so on. In addition, integrins also play an important role in heart development, growth and response to pathophysiological signals. Effort