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目的:观察宁心解郁汤治疗糖尿病抑郁症的临床疗效。方法:将80例糖尿病抑郁症患者随机分为治疗组(口服宁心解郁汤合并氟西汀)和对照组(口服氟西汀)各40例,分别于治疗前、治疗4周后根据汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)、症状自评量表(SCL-90)评定两组患者临床症状、心理及躯体障碍的变化。结果:治疗后两组抑郁症患者的临床症状和心理、躯体障碍均得到了改善,与本组治疗前比较差异有统计学意义(P<0.05),治疗组疗效优于对照组(P<0.05)。结论:宁心解郁汤联合氟西汀治疗糖尿病抑郁症疗效可靠,可以较好地改善临床症状。
Objective: To observe the clinical efficacy of Ningxin Jieyu Decoction in the treatment of diabetic depression. Methods: Eighty diabetic patients with diabetes mellitus were randomly divided into treatment group (oral Ningxuyutang combined with fluoxetine) and control group (oral fluoxetine), 40 cases each before treatment and 4 weeks after treatment, HAMD, SDS and SCL-90 were used to assess the changes of clinical symptoms, psychological and physical disorders in the two groups. Results: After treatment, the clinical symptoms and psychological and physical disorders of the two groups of patients with depression were improved. There was significant difference between the two groups before treatment (P <0.05), and the treatment group was better than the control group (P <0.05) ). Conclusion: Ningxin Jieyu decoction combined with fluoxetine in the treatment of diabetic depression is reliable and can improve clinical symptoms.