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在体外试验中特定黑色素启抗原（melanomaantigen，MA）的接种能大大增强细胞毒性T淋巴细胞（CT）的作用，但在临床应用中，这种接种并不能有效抑制肿瘤生长。这使人们对接种诱导的CTL的临床效应产生了疑问。作者认为，特定抗原决定读的接种能激活HLA限制的T淋巴细胞，后者能选
Vaccination with a specific melanomantigen (MA) in vitro significantly enhanced the cytotoxic effect of cytotoxic T lymphocytes (CTs), but in clinical practice this inoculation did not effectively inhibit tumor growth. This cast doubt on the clinical effect of vaccination-induced CTL. Authors believe that vaccination with specific antigenic determinations can activate HLA-restricted T lymphocytes, which can be selected