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取100μl正常人血浆在体外制成0.5～0.8mm大小的血栓颗粒,自猪颈内动脉注入颅内,用DSA观察栓塞部位,24h后作病理检查.结果:猪的颈内动物入颅前先形成网状结构,再合成一主干分出颅内各分支,血栓均受阻于网前或网中.栓塞成功率100%,6h后脑血管造影栓子未溶解,病理示5例出现脑梗死.结论:该模型栓塞部位固定、成功率高,能用DSA作为可靠的观察指标,可用于评价溶栓疗效.
Take 100μl of normal human plasma in vitro made of 0.5 ~ 0.8mm size thrombus particles, injected into the brain from the pig’s internal carotid artery, DSA observation embolization site, 24h after pathological examination.Results: Pig’s internal carotid artery into the skull The formation of a network structure, and then the synthesis of a branch of the brain branches of the intracranial, thrombosis were blocked in the mesh or the network.Embolization success rate of 100%, 6h after cerebral angiography emboli did not dissolve pathology showed cerebral infarction in 5 cases.Conclusion : This model embolization site fixed, high success rate, DSA can be used as a reliable indicator, can be used to evaluate thrombolytic efficacy.