论文部分内容阅读
目的研究分析胃癌手术后感染发生的危险因素。方法回顾性分析2005年2月至2012年2月间收治的400例胃癌手术后患者,统计分析患者术后感染发生率与相关因素的相关性。结果胃癌术后感染率与年龄大小、吸烟年支多少、手术范围、术前预防性抗生素应用、术前输血量、白细胞水平、Th细胞水平、病理分期和住院时间有关,另外BMI过小者比正常和偏胖者感染率更高,差异有统计学意义(P<0.05);随着年龄的增长、吸烟年支的增加、手术范围的扩大、输血量的增加、Th细胞水平的降低和病理分期的延后,胃癌患者术后感染率上升;年龄、吸烟、手术范围、输血量和病理分期是影响术后感染率的独立危险因素,其中术前输血量的相对危险度最高(P<0.05)。结论可以从年龄大小、吸烟年支多少、手术范围、术前预防性抗生素应用、术前输血量、白细胞水平、Th细胞水平、病理分期和住院时间多方面考虑降低胃癌患者术后的感染率。
Objective To study the risk factors of infection after gastric cancer surgery. Methods A retrospective analysis of 400 patients with gastric cancer admitted between February 2005 and February 2012 was performed to statistically analyze the correlation between the incidence of postoperative infection and related factors. Results The postoperative infection rate of gastric cancer was related to the age, the number of years of smoking, the scope of surgery, preoperative prophylactic antibiotics, blood transfusion, leukocyte level, Th cell level, pathological stage and length of hospital stay. The infection rate of normal and overweight people was higher, the difference was statistically significant (P <0.05). With the increase of age, the increase of smoking year branch, the expansion of operation scope, the increase of blood transfusion, the decrease of Th cell level and pathology The postoperative infection rate of patients with gastric cancer increased; age, smoking, surgical range, blood transfusion volume and pathological stage were independent risk factors influencing postoperative infection rate, of which the relative risk of preoperative blood transfusion was the highest (P <0.05 ). Conclusions The postoperative infection rate of patients with gastric cancer can be considered in many aspects such as the age, the number of years of smoking, the scope of the operation, the application of preoperative prophylactic antibiotics, the volume of blood transfusion, the level of leukocytes, the level of Th cells, the pathological stage and the length of hospital stay.