目的　调查中国碘盐普及地区新生儿脐带血促甲状腺激素 (TSH)水平 ,提出新生儿脐带血TSH的正常值范围 ,并探讨该指标的应用。方法　选取普及碘盐且孕妇碘营养情况良好的 7省市 ,采集孕妇尿样及其新生儿脐带血血样 ,测定孕妇尿碘和新生儿脐带血TSH值。结果　共测定15 2 4名孕妇的尿碘及其新生儿脐带血TSH值 ,结果显示孕妇尿碘中位数为 2 4 6 .0 μg L ,新生儿脐带血TSH中位数为 3.5 8mU L ;不同地区、不同分娩方式的新生儿脐带血TSH水平差异存在显著性。结论　新生儿脐带血TSH受应激反应和分娩方式等诸多因素影响 ,且不具规律性 ,尚难以确定其正常值范围 ,因此不宜作为碘缺乏病监测指标 ,但可继续用于新生儿甲状腺机能减低的筛查 Objective To investigate the level of thyroid hormone (TSH) in cord blood of newborn infants in the popularization area of ​​iodized salt in China and to put forward the normal range of TSH in neonatal cord blood and to explore the application of this index. Methods Seventy provinces and cities with iodized salt and iodine nutrition in pregnant women were selected to collect urine samples from pregnant women and umbilical cord blood samples of their newborns and to determine urinary iodine and neonatal umbilical cord blood TSH values. Results A total of 15424 pregnant women were tested for urinary iodine and neonatal umbilical cord blood TSH values. The median urinary iodine was 24.06 μg in pregnant women and 3.58 mU L in neonates with cord blood. Different regions, different modes of delivery neonatal cord blood TSH levels were significant differences. Conclusion Neonatal umbilical cord blood TSH is affected by many factors, such as stress response and mode of delivery, and is not regular. It is difficult to determine the normal range of TSH, so it should not be used as an indicator of iodine deficiency disorders, but can continue to be used in neonatal hypothyroidism Screening