Arylamine N-acetyltransferase (NAT;E.C.2.3.1.5) enzymes are responsible for the biotransformation of several arylamine and hydrazine drugs by acetylation.In thi
Blocking the MDM2/X-P53 protein-protein interaction has been widely recognized as an attractive therapeutic strategy for the treatment of cancers.Numerous small
The dense extracellular matrix and high interstitial fluid pressure of tumor tissues prevent the ability of anti-tumor agents to penetrate deep into the tumor p