Fibroblast growth factors (FGFs) make up a large family of polypeptide growth factors that are found in organisms ranging from nematodes to humans.In vertebrates, a number of FGFs have been shown to play important roles in developing embryos and adult organisms.Among vertebrate species,FGFs are highly conserved in both gene structure and amino acid sequence.However, studies on teleost FGFs are mainly limited to model species, then we launched the excavations of FGFs in common carp genome.We identified a set of 36 FGFs in common carp genome.Phylogenetic analysis revealed that most of the FGFs are highly conserved, though recent gene duplication and gene losses do exist.Through examining the copy number of FGFs across several vertebrate genomes, nine FGFs in common carp are found to have undergone the gene duplications, including FGF6a, FGF6b, FGF7, FGF8b, FGF10a, FGF11b, FGF13a, FGF18b, and FGF23.The expression patterns of all FGFs were established in various tissues, including blood, brain, gill, heart, intestine,muscle, skin, spleen, and kidney, and showed that most of the FGFs were ubiquitously expressed,indicating the critical role of FGFs in common carp.To some extent, examination of gene families with detailed phylogenetic or orthology analysis could verify the authenticity and accuracy of assembly and annotation of the recently-published common carp whole genome sequences.The gene families are also considered as a unique source for evolutionary studies.Moreover, the whole set of common carp FGFs gene family provides an important genomic resource for future biochemical,physiological, and phylogenetic studies of fibroblast growth in teleost.