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Department of plastic surgery,Jinling Hospital,Medical school of Nanjing University,Nanjing 210002,Jiangsu,ChinaBackground:Infantile hemangioma grows quickly in the first year of life and regresses slowly to fibrofatty tissue in the childhood.Mesenchymal stem cells (MSCs) were reported to contribute to the adipogenesis in hemangioma involution.Late studies showed the perivascular origin of MSCs in multiple organs.We hypothesized that MSCs in hemangioma might also reside in the perivascular region.