Germ cell differentiation from induced pluripotent stem cells

来源 :中国细胞生物学学会全体会员代表大会暨第十二次学术大会 | 被引量 : 0次 | 上传用户:wajohn
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Historically, our understanding of molecular genetic aspects of germ cell development has been limited.Recently, results have demonstrated that the derivation of pluripotent stem cells may provide the necessary genetic system to study germ cell development.Here, we first characterized an induced pluripotent stem cells (iPSCs) line, which stably carried an pOct4-EGFP1 recombinant plasmid that expressed green fluorescent protein (GFP) under the control of Oct4 promoter, to confirm the pluripotent characteristic maintained.
其他文献
会议
  泛素结合酶基因UbcM2是一个生长抑制基因,其编码的蛋白参与泛素蛋白水解酶系统并在成年小鼠的各组织中广泛表达.本研究通过实时定量RT-PCR及原位杂交技术,对小鼠UbcM2基
  Epidermal growth factor (EGF) plays a role in male germ cell development, but the precise function is yet to be defined.The present study shows that EGF sti
会议
  Lung morphogenesis is a well-orchestrated, tightly regulated process through several molecular pathways including TGF/BMP signaling.Alteration of these sign
会议
  我们实验室之前的研究发现,低浓度的小分子化合物黄樟素氧化物(safrole oxide,SFO)可以诱导人脐静脉血管内皮细胞(HUVEC)转分化为神经元样细胞,但是SFO是否同样可以诱导
会议
园林工程是一个较为复杂的综合工程。长期以来不注重绿地生态功能的发挥,不注重成本核算,重建轻管,导致绿化成本高,绿地景观效果差,生态功能弱化,碳排放倍增。本文从以低能耗