目的　探讨蛾类抗原与变态反应性疾病的相关性。方法　应用人工饲养的米蛾抗原对 30 0例变态反应性疾病患者进行皮肤试验及血清特异性IgE检测。结果　 30 0位受检的患者中 ,皮肤试验阳性者共 94人 ,阳性率 31.33%。血清特异性IgE阳性 131人 ,阳性率为 4 3.6 6 %。结论　变态反应性疾病患者蛾抗原皮肤试验和血清特异性IgE阳性率均明显高于对照组 ,证实蛾类是变态反应性疾病常见的致敏原 ,二种检测方法是检测蛾致敏的有效方法 ,两者间有显著相关性 (P <0 .0 0 5 ,χ2 =110 6 .2 2 ) ,阳性率有显著差异 (P <0 .0 0 5 ,χ2 =14 .2 4 ) ,提示皮试结果有可能受其它因素的影响 ,而血清特异性IgE检测特异性更强、更安全、可靠 Objective To investigate the relationship between moth antigen and allergic diseases. Methods Skin tests and serum specific IgE were performed on 300 patients with allergic diseases using artificial moth moth antigen. Results Among the 30 subjects tested, 94 were skin test positive, with a positive rate of 31.33%. Serum-specific IgE-positive 131 people, the positive rate was 43.6%. Conclusions Moth antigen skin tests and serum specific IgE positive rates in patients with allergic diseases were significantly higher than those in the control group, confirming that moths are common allergens in allergic diseases. The two detection methods are effective methods to detect the sensitization of moths (P <0.05, χ2 = 1106.22), the positive rate was significantly different (P <0.05, χ2 = 14.24), suggesting that the skin Test results may be affected by other factors, and serum-specific IgE detection more specific, more secure, reliable