Capillary electrophoresis (CE) is widely used in chiral separation of drug for its high sensitivity, low sample consumption, outstanding separation capability for fast analysis.Cyclodextrin (CD) and its derivatives are widely used as chiral selectors in CE for the enantiomeric separation of racemic drug thanks to their aqueous solubility and good chiral resolution ability.Development of structurally well-defined charged CDs is attracting due to the extra electrostatic interaction contribution for the oppositely charged racemates [1-3].