The Activity of Hybrid Vector-mediated Interleukin-24 for Oral Carcinoma Drug Resistant Cells

来源 :2014xi`an Conference of International Society for Maxillofac | 被引量 : 0次 | 上传用户：flyfish11111

【摘要】

：

　　Purpose: Evaluate the potential therapeutic effect of IL-24 against KB(human oral squamous cell carcinoma cells line)and KBv(Vincristine resistant KB cells

【作者】

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YangDezhao;

【机构】

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Department of Oral and Maxillofacial Surgery,The First Affiliated Hospital of Harbin Medical Univers

【出处】

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2014xi`an Conference of International Society for Maxillofac

【发表日期】

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2014年期

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　　Purpose: Evaluate the potential therapeutic effect of IL-24 against KB(human oral squamous cell carcinoma cells line)and KBv(Vincristine resistant KB cells line).To seek a new way for the therapy of drug resistant oral carcinoma.Methods: KB(human oral squamous cell carcinoma)and KBv(vincristine resistant KB cell line)were utilized in this study.The human keratinocyte cell line HaCaT was used as a positive control for receptor detection.Apoptosis induced by IL-24 in human oral squamous cell carcinoma cell line(KB and KBV)was measured using the MTT assay,flow cytometry,Caspase-Glo(R)3/7 assay and Western Blot assay.

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