OBJECTIVE: This study aimed to investigate the health status, quality of life and chronic diseases of centenarians and to discuss factors affecting their longevity in Zhongxiang, Hubei.METHODS: Severa
OBJECTIVE: Cisplatin is the first-line chemotherapy for the treatment of non-small cell lung cancer (NSCLC).However, its resistance has been a major obstacle in the management of NSCLC.Aldehyde dehydr
The Case: Upper Gastrointestinal (UGI) bleeding treated with acid suppression increase the risk of Clostridium Difficile Colitis (CDC).An 85 year-old Chinese male, with hypertension and Type2 DM, had
OBJECTIVE: This study aimed to analyze the characteristics of brachial-ankle pulse wave velocity (baPWV) between different genders and to investigate its influencing factors in elderly population.METH
OBJECTIVE: This study aimed to investigate the factors associated with decreased ability of daily life in elderly patients with chronic kidney disease.METHODS: A cross-sectional study was conducted be
OBJECTIVE: This study aimed to explore the relationships of serum levels of visfatin andMMP-9 with insulin resistance (IR).in patients with coronary heart disease (CHD).METHOD: Eighty patients who had
OBJECTIVE: This study aimed to compare the effects of different dosage of oxycodone hydrochloride injection with propofol on elderly patients undergoing therapeutic ERCP.METHODS: Ninety elderly patien
BACKGROUND: Beta amyloid (Aβ) is believed to be a key pathological hallmark of Alzheimer disease (AD) and the identification of the involved biological process or pathway is considered to be a primary
患者女,84岁.双眼视物不清10余年,近来左眼视力下降明显.查视力:右眼0.12,左眼0.5,双眼矫正视力不提高.双眼前节未见明显异常,双眼晶体混浊,以右眼为重,左眼玻璃体腔内可见絮状混浊物,右眼眼底检查:视盘边界清楚,视网膜血管走形大致正常,黄斑区见一约2DD大小的黄色圆形病灶.左眼眼底检查:视盘边界清楚,视网膜血管走形正常,中心凹反光不见.右眼红外照相示黄斑区可见一约2PD大小的弱荧光;荧光素
目的 研究12个中国人XLRS家系及检测到的11种XLRSI基因突变与临床表现型的关系.方法 对12个XLRS家系的28例男性患者及女性携带者和正常对照者分别进行详细的眼科检查,包括视力、屈光度、裂隙灯及眼底检查,部分患者行全视野视网膜电图(ERG)、眼底血管造影、光学相干断层扫描(OCT)及A/B型超声检查.采用聚合酶链反应(PCR)和单链构象多态性(SSCP)分析,对XLRSI基因突变进行筛查