Objectives:In order to estimate the current prevalence of hypertension,cardiovascular condition and hearing difficulty of workers who have been exposed to occupational noise for many years,and to examine any associations between these outcomes and occupational noise exposure,we investigated and analyzed data from occupational,physical examinations.[Methods] The subjects included 5205 noise-exposed workers(1041 high exposure and 4174 low exposure)from factories in Nanjing city.Health status was evaluated in all subjects by clinical and laboratory examination,which was performed after a face-to-face interview.In our study,a sound pressure individual audiometer was used in the proper place and time using the appropriate methods to evaluate the real working environment.All participants underwent a tonal audiometric examination that was performed in a sound isolation cabinet by a trained technician.All of the data were entered into a computerized database.Analyses were performed using the statistical analysis software SAS 9.1.3 with the significance level set at 0.05 for all tests.[Results] Of the subject included,93.76%were male,the mean age was 37.23±9.11 years,and the exposure time to noise was 5.31±5.28 years on average.There was no significant difference between low and high noise exposure individuals regarding age,sex and exposure time to noise.However,subjects with high noise exposure were more likely to have a higher threshold value than low exposure ones(P <0.05).Workers in the high exposure group had a significantly higher risk of hypertension and hearing loss than the workers in the low exposure group; P value was 0.047 for hypertension and 0.003 for hearing loss.Unfortunately,there was no significant difference found in the distribution of ECG between the two exposure groups(P=0.573).Between the ages of 30 and 45,a history of high-level occupational noise exposure led to a significantly elevated risk of both hypertension(Adjusted OR =1.59,95%CI,1.19-2.11)and hearing loss(Adjusted OR =1.28,95%CI,1.03-1.60)when comparing to low-level noise exposure.In male workers,the prevalence of hearing difficulty in the high exposure group was approximately 1.2 times higher than in the low exposure group(P=0.006),which was not the case in female workers.In addition,exposure to high noise level demonstrated a significant association with hypertension and hearing loss when the duration time to occupational noise was longer than 10 years.[Conclusions] Hypertension and hearing difficulty is more prevalent among the noise-exposed group(higher than 85dB[A]).Steps to reduce workplace noise levels in the Nanjing area are thus urgently needed.In addition,workplace-based health and wellness programs should also be considered.