2. 您的位置
3. 首页
4. 会议论文
5. Multifunctional unimolecular micelles for targeted cancer therapies

Multifunctional unimolecular micelles for targeted cancer therapies

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：pb8

【摘 要】

：

Drug nanocarriers are of great interest in targeted cancer therapy due to their passive (via the enhanced permeability and retention (EPR) effect) and active (via cell-specific ligand conjugation) tum

【作 者】

：

Shaoqlin Gong Guojun Chen Renata Jaskula-Sztul Ashley M.Brinkman Wei Xu Herbert Chen 

【机 构】

：

Department of Biomedical Engineering,Materials Science and Engineering,and Wisconsin Institute for D

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

unimolecular micelles targeted cancer therapies drug nanocarrier controlled rele 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Drug nanocarriers are of great interest in targeted cancer therapy due to their passive (via the enhanced permeability and retention (EPR) effect) and active (via cell-specific ligand conjugation) tumor-targeting capabilities[1].

其他文献

辊压设备自动化水平的提升

会议

Self-assembled supramolecular nanosystems for smart targeted therapy of intractable diseases

Nanotechnology-based medicine (Nanomedicine) has received progressive interest for the treatment of intractable diseases,such as cancer,as well as for the non-invasive diagnosis through various imagin

会议

nanomedicineself-assembled nanosystemspolymeric micellescancermRNA

Design of functional micelles for enhanced cellular uptake and their analysis in cancer spheroids

Micelles and vesicles have long been proposed as carriers for low molecular weight molecules including drugs.The ability of micelles to deliver drug is usually tested by incubating them with a monolay

会议

micellesglycopolymersproteinsdrug deliverymulticellular cancer spheroids

Engineering smart hybrid nanocontainers for on-demand delivery

New generations of organic-inorganic porous hybrid materials are fabricated by combining covalent bonding with non-covalent or supramolecular interactions.Studies on the molecular levels are performed

会议

mesoporous silica nanoparticleshybrid organosilica nanoparticlescolloidosomes

Affinity controlled release

Controlled release of protein therapeutics is particularly challenging due to the complexity of protein structure,which is often denatured by the typical organic solvents and shear forces typically us

会议

affinity controlled releaseprotein-peptide binding partnerselectrostatic inter

Targeted polymeric nanoparticles:From discovery to clinical trials

A variety of organic and inorganic materials have been utilized to generate nanoparticles for drug delivery applications,including polymeric nanoparticles,dendrimers,nanoshells,liposomes,nucleic acid

会议

nanoparticletargeted therapydrug deliverybiogradable polymers

Controlled local drug delivery by various thermo-responsive hydrogels

For in situ thermo-sensitive hydrogel,it is a big challenge to achieve high drug loading,long-term local retention and effective drug release simultaneously.Firstly,we investigated thermo-sensitive Pl

会议

controlled drug deliverythermo-responsivehydrogellocal injection

Multivalent nanosystems as anti-inflammatory and antiviral drugs

会议

Engineering intracellular delivery nanocarriers and nanoreactors from oxidation-responsive polymerso

Reactive oxygen species (ROS) and oxidative stress are implicated in various physiological and pathological processes and this feature provides a vital biochemical basis for designing novel therapeuti

会议

oxidation-responsivepolymersomesbilayer permeabilityin vivo nanoreactors

Bioactive glycopolypeptide self-assembled biohybrid nanomaterials

The field of synthetic polypeptides has seen many significant advances in recent years,including studies on block and hybrid copolypeptides that form vesicles,fibrils,and other structures with potenti

会议

block copolymersself-assemblyglycopolymerspolymersomes