Displaced ganglion cell in the mouse retina

来源 :中国神经科学学会第九届全国学术会议暨第五届会员代表大会 | 被引量 : 0次 | 上传用户:voodoochildzm
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  Objective This study represents the most complete morphological classification of mouse retinal displaced ganglion cells (DGCs) in the inner nuclear layer available to date and provides a foundation for further understanding of the correlation of physiology and morphology and ganglion cell function with genetically manipulated animals.Methods (1) Flurogold was injected in two adjacent sites or one left site at the SC and the soma of DGCs in the mouse retina was stained by retrograding with Flurogold.(2) The morphology of DGCs was revealed by microinjection with Lucifer yellow.(3) The diameter of soma and dendritic field and distance from soma to the optic nerve were measured.Results (1) The diameter of soma (or dendritic field) and distance from soma to the optic nerve were irrelevant.(2) The DGCs were classified into five groups based on their soma size, dendritic field size, and pattern and level of stratification.Conclusion (1) It was proved that all morphological types of GCs in the GCL also existed in the INL.(2) For monostratified DGCs, there is similar distribution of four morphological types in contralateral projection group and significant preference of B and C types in ipsilateral projection group.
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