【摘 要】
：
Haimiding is a compound anticancer preparation combining Chinese and Western medicine.It is parepared from the anticancer drug 5-Fu (5-fluorouracil) plus ex
【机 构】
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Postdoctoral Research Station, Institute of Materia Medica, Harbin Commercial University, Harbin 150
【出 处】
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2005 WHTS'3rd Annual Congress of International Drug Disc
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Haimiding is a compound anticancer preparation combining Chinese and Western medicine.It is parepared from the anticancer drug 5-Fu (5-fluorouracil) plus extracts from Chinese medicines including Sargassumfusiforme, Ecklonia kurome, Astragalus chrysopterus, and Sophoraflarescens.Findings from our earlier studies show that Haimiding has some killing power on 8 kinds of human cancerous cells, namely, human oral epithelial KB, human esophageal carcinoma ECA-109, human proventriculas BGC-823, human pulmonary adenocarcinoma A549, human colon HCT-8, human breast MCF-7,human ovary A2780, and human liver Bel-7402.Its inhibitory effect is the most prominent on BGC-823, EcA-109, and HCT-8 cells.It clearly can inhibit the formation ofBGC-823, EcA-109, and HCT-8 colonies, with the effect on EcA-109 colonies being the strongest.It has a clear inhibitory effect on the growth of FC tumors in mice, and can significantly prolong the life span of H22 tumor-bearing mice.
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