Inflammation is a critical component involved in tumor progression.IL-17 cytokine family, though still young since discovery, has recently emerged as import
Background: The close interaction between tumor cells and the bone marrow microenvironment plays a pivotal role in the tumorigenesis of multiple myeloma (MM
Optical molecular imaging is the most promising tools for investigating the function and motility of immune cells in vivo.We have developed a multi-scale op
Introduction: Colorectal cancer is a serious threat to human health.And metastasis is the key factor of poor prognosis.Recently, we have found that the nega
Object: Tumor associated macrophages (TAMs) play critical roles in promoting tumor progression and invasion.However, the molecular mechanism for the regulat
Absent in melanoma 2 (AIM2) is an innate immune receptor for double-strand DNA from viruses and cytosolic bacteria and is well known to form inflammasome.
Background: Immune cells are believed to participate in initiating anti-tumor effects during regular tumor therapy such as chemotherapy, radiation, hyperthe